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Total Synthesis of Norsampsones A and B, Garcinielliptones N and O, and Hyperscabrin A 期刊论文

编号：

e9ff27db-d8e2-4b21-8dd6-e7451258aacd
作者：

Zheng, Changwu(郑昌武)#^[1]Wang, Xueying#^[1]Fu, Wenwei(付文卫)^[1]Lu, Yue^[1]Tan, Hongsheng(谭红胜)*^[1]Xu, Hongxi(徐宏喜)*^[1]
语种：

英文
期刊：

JOURNAL OF NATURAL PRODUCTS ISSN：0163-3864 2018 年 81 卷 11 期 (2582 - 2589) ; NOV
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摘要：

The asymmetric total synthesis of five decarbonyl polycyclic polyprenylated acylphloroglucinols norsampsnes A (3) and B (4), garcinielliptones O (5) and N (6), and hyperscabrin A (7) is described. The synthesis to construct the core substituted cyclohexanone ring of these natural products was achieved by a key Dieckmann condensation. The chirality of the molecules was introduced by the stereoselective alkylation with Evans' oxazolidinones. The synthesis could be run on grams scale, and the Dieckmann condensation was investigated through the DFT calculations to help improve the yield of garcinielliptone O (5). Determination of the absolute configuration of garcinielliptones O (5) and N (6) was also achieved.
推荐引用方式
GB/T 7714：

Zheng Changwu,Wang Xueying,Fu Wenwei, et al. Total Synthesis of Norsampsones A and B, Garcinielliptones N and O, and Hyperscabrin A [J].JOURNAL OF NATURAL PRODUCTS,2018,81(11):2582-2589.
APA：

Zheng Changwu,Wang Xueying,Fu Wenwei,Lu Yue,&Xu Hongxi.(2018).Total Synthesis of Norsampsones A and B, Garcinielliptones N and O, and Hyperscabrin A .JOURNAL OF NATURAL PRODUCTS,81(11):2582-2589.
MLA：

Zheng Changwu, et al. "Total Synthesis of Norsampsones A and B, Garcinielliptones N and O, and Hyperscabrin A" .JOURNAL OF NATURAL PRODUCTS 81,11(2018):2582-2589.
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