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NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula 期刊论文

编号：

e7f35862-841c-4c36-9711-5f9a5d0bdc73
作者：

Luo, Yingbin(骆莹滨)#^[1]Wu, Jianchun(吴建春)^[1]Zhu, Xiaowen(祝晓雯)^[2]Gong, Chenyuan(龚陈媛)^[2]Yao, Chao^[2];Ni, Zhongya^[2];Wang, Lixin(王莉新)^[2]Ni, Lulu^[2];Li, Yan*^[1]Zhu, Shiguo(朱诗国)*^[2,3]
语种：

英文
期刊：

MEDIATORS OF INFLAMMATION ISSN：0962-9351 2016 年 2016 卷
收录：
摘要：

Little is known about Yu-Ping-Feng (YPF), a typical Chinese herbal decoction, for its antitumor efficacy in non-small-cell lung cancer (NSCLC). Here, we found that YPF significantly inhibited the growth of Lewis lung cancer, prolonged the survival of tumor-bearing mice, promoted NK cell tumor infiltration, increased the population of NK cells in spleen, and enhanced NK cell-mediated killing activity. The growth suppression of tumors by YPF was significantly reversed by the depletion of NK cells. Furthermore, we found that YPF significantly downregulated the expression of TGF-beta, indoleamine 2,3-dioxygenase, and IL-10 in tumor microenvironment. These results demonstrated that YPF has a NK cell-dependent inhibitory effect on Lewis lung cancer.
推荐引用方式
GB/T 7714：

Luo Yingbin,Wu Jianchun,Zhu Xiaowen, et al. NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula [J].MEDIATORS OF INFLAMMATION,2016,2016.
APA：

Luo Yingbin,Wu Jianchun,Zhu Xiaowen,Gong Chenyuan,&Zhu Shiguo.(2016).NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula .MEDIATORS OF INFLAMMATION,2016.
MLA：

Luo Yingbin, et al. "NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula" .MEDIATORS OF INFLAMMATION 2016(2016).
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