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Anthraquinones from the Roots of Knoxia valerianoides and their Anticancer Activity 期刊论文

编号：

d5d69cc2-4565-4b9c-96f3-bd9d15224fb0
作者：

Yang, Xuan^[1,2,3];Chou, Guixin(侴桂新)^[1,2,3]Ji, Lili(季莉莉)^[1,2,3]Han, Liting^[1,2,3];Zhu, Enyuan(朱恩圆)*^[1,2,3]
语种：

英文
期刊：

LATIN AMERICAN JOURNAL OF PHARMACY ISSN：0326-2383 2013 年 32 卷 1 期 (96 - 100)
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关键词：

Anthraquinones Cytotoxic activity Cdc25B Hep3B Knoxia valerianoides
摘要：

Anticancer compounds from the roots of Knoxia valerianoides Thorel et Pitard were investigated. Two anthraquinones, damnacanthol-omega-ethyl ether (1) and 3-hydroxy-2-hydroxymethyl anthraquinones (2) were isolated for the first time, along with seven other anthraquinones, lucidin (3), rubiadin (4), 3-hydroxymorindone (5), damnacanthol (6), nordamnacanthal (7), konxiadin (8) and 2-ethoxy-methylknoxiavaledin (9). Three of these anthraquinones (compounds 3-5) showed remarkable cytotoxicity against human hepatoma Hep3B cells, human gastric cancer AGS cells and human breast cancer MDA-MB-231 cells but had no significant effects human normal liver L-02 cells. And they also performed inhibitory activities on cell division cycle 25B (Cdc25B) phosphatase.
推荐引用方式
GB/T 7714：

Yang Xuan,Chou Guixin,Ji Lili, et al. Anthraquinones from the Roots of Knoxia valerianoides and their Anticancer Activity [J].LATIN AMERICAN JOURNAL OF PHARMACY,2013,32(1):96-100.
APA：

Yang Xuan,Chou Guixin,Ji Lili,Han Liting,&Zhu Enyuan.(2013).Anthraquinones from the Roots of Knoxia valerianoides and their Anticancer Activity .LATIN AMERICAN JOURNAL OF PHARMACY,32(1):96-100.
MLA：

Yang Xuan, et al. "Anthraquinones from the Roots of Knoxia valerianoides and their Anticancer Activity" .LATIN AMERICAN JOURNAL OF PHARMACY 32,1(2013):96-100.
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