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The influence of different debridement methods on the prognosis of elderly patients with diabetic foot ulcers and sepsis 期刊论文

编号：

c56f7c6e-c864-476d-9d47-e5a3c7ef976f
作者：

Yang, Qintong(杨沁彤)#^[1]Cao, Yemin(曹烨民)*^[1]Fang, Yudong(方豫东)^[1]Li, Bin(李斌)^[1]Zhao, Puqing^[2];Wang, Weiling^[3];Yin, Lingfeng(尹凌峰)^[1]Xu, Hongtao^[1];Hu, Gaowu^[4];
语种：

英文
期刊：

MINERVA CHIRURGICA ISSN：0026-4733 2017 年 72 卷 3 期 (200 - 205) ; JUN
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关键词：

Diabetic foot Debridement Sepsis Mortality
摘要：

BACKGROUND: We evaluated the influence of different debridement methods on the prognosis of elderly patients with diabetic foot ulcers complicated with sepsis.
METHODS: Retrospective study was adopted to study 65 hospitalized elderly patients with Wagner Grade-4 diabetic foot ulcer and sepsis in Vascular Disease Department of Shanghai TCM-Integrated Hospital. Thirty-two cases were included in the thorough debridement group and the other 33 were included in the minor debridement group. We compared the mortality rates on the 7th day and 14th day after debridement, and monitored changes of sepsis-related organ failure assessment (SOFA) Score as well as C-reactive protein (CRP), procalcitonin (PCT) and D-Dimer (D-D) levels. Cox regression analysis and Kaplan-Meier analysis were used to analyze the mortality rates. Binary logistic regression analysis was employed to screen relevant prognostic factors to see the prognostic value of SOFA Score, PCT and D-D.
RESULTS: Fatality rates of the thorough debridement group on the 7th day and 14th day of the debridement were higher than those in the minor debridement group and such a difference has statistical significance. The CRP, PCT, and D-D of patients within seven days after thorough debridement were obviously higher than those of patients after minor debridement.
CONCLUSIONS: Damage control should be provided for elderly patients with diabetic foot ulcers and sepsis when debridement is being performed. Palliative debridement methods such as small-scale incision and drainage are less likely to affect systematic inflammatory response and coagulation function, and thus can buy time for further treatment to improve clinical effect.
推荐引用方式
GB/T 7714：

Yang Qintong,Cao Yemin,Fang Yudong, et al. The influence of different debridement methods on the prognosis of elderly patients with diabetic foot ulcers and sepsis [J].MINERVA CHIRURGICA,2017,72(3):200-205.
APA：

Yang Qintong,Cao Yemin,Fang Yudong,Li Bin,&Hu Gaowu.(2017).The influence of different debridement methods on the prognosis of elderly patients with diabetic foot ulcers and sepsis .MINERVA CHIRURGICA,72(3):200-205.
MLA：

Yang Qintong, et al. "The influence of different debridement methods on the prognosis of elderly patients with diabetic foot ulcers and sepsis" .MINERVA CHIRURGICA 72,3(2017):200-205.
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