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The Hippo Signaling Pathway: an Emerging Anti-cancer Drug Target 期刊论文

编号：

90981048-89f5-4199-9453-74d6c8b8dc4e
作者：

Tao, Yuquan^[1];Cai, Feng(蔡枫)^[2]Shan, Liang^[1];Jiang, Hongyuan^[1];Ma, Lifang^[2];Yu, Yongchun^[1];
语种：

英文
期刊：

DISCOVERY MEDICINE ISSN：1539-6509 2017 年 24 卷 130 期 (7 - 18) ; AUG
收录：
摘要：

The Hippo signaling is a highly conserved pathway that plays important roles in tumorigenesis, stem cell self-renewal and differentiation, organ size control, and many other biological processes. Functions of the Hippo signaling pathway are regulated by complicated intracellular and extracellular signaling networks. When activated, the Hippo pathway functions as a tumor suppressor. However, dysregulation of this pathway contributes to increased cell proliferation and decreased apoptosis and differentiation. Therefore, regulation of Hippo signaling by pharmacological modulators may be a promising anticancer strategy. Here, we summarize potential anti-cancer drugs that target components of the Hippo pathway or regulate interactions between the Hippo signaling pathway and other signaling pathways.
推荐引用方式
GB/T 7714：

Tao Yuquan,Cai Feng,Shan Liang, et al. The Hippo Signaling Pathway: an Emerging Anti-cancer Drug Target [J].DISCOVERY MEDICINE,2017,24(130):7-18.
APA：

Tao Yuquan,Cai Feng,Shan Liang,Jiang Hongyuan,&Yu Yongchun.(2017).The Hippo Signaling Pathway: an Emerging Anti-cancer Drug Target .DISCOVERY MEDICINE,24(130):7-18.
MLA：

Tao Yuquan, et al. "The Hippo Signaling Pathway: an Emerging Anti-cancer Drug Target" .DISCOVERY MEDICINE 24,130(2017):7-18.

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