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Three new alkaloids from Xylopia vielana and their antiinflammatory activities 期刊论文

编号：

795b3acf-8c11-4f55-bbaf-6639f1b5e4d5
作者：

Guo, YiGong#^[1]Ding, YunHe#^[1]Wu, GuoJing^[1];Zhu, ShengLan^[1];Sun, YuanFang^[1];Yan, ShiKai^[1];Qian, Feng*^[1]Jin, HuiZi*^[1]Zhang, WeiDong*^[1,2,3]
语种：

English
期刊：

FITOTERAPIA ISSN：0367-326X 2018 年 127 卷 (96 - 100) ; JUN
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关键词：

Alkaloids Xylopia vielana Antiinflammatory activities
摘要：

Three new aporphine alkaloids, xylopialoids A-C (1-3), along with three known aporphine alkioids (4-6) and three other known compounds (7-9) were isolated from the roots of Xylopia vielana. Among these three new aporphine alkaloids, xylopialoid C (3) showed a special carbamido group directly connected to the nitrogen. The chemical structures of these nine compounds were determined by a combination of 1D and 2D NMR, MS, CD spectrum and Cu K alpha X-ray crystallographic analyses. All these six alkaloids were firstly tested for the inhibitory activities against the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). Among these compounds, 4 showed a potential inhibitory activity against the production of nitric oxide with IC50 value of 1.39 mu M.
推荐引用方式
GB/T 7714：

Guo Yi-Gong,Ding Yun-He,Wu Guo-Jing, et al. Three new alkaloids from Xylopia vielana and their antiinflammatory activities [J].FITOTERAPIA,2018,127:96-100.
APA：

Guo Yi-Gong,Ding Yun-He,Wu Guo-Jing,Zhu Sheng-Lan,&Zhang Wei-Dong.(2018).Three new alkaloids from Xylopia vielana and their antiinflammatory activities .FITOTERAPIA,127:96-100.
MLA：

Guo Yi-Gong, et al. "Three new alkaloids from Xylopia vielana and their antiinflammatory activities" .FITOTERAPIA 127(2018):96-100.
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