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Xylopidimers A-E, Five New Guaiane Dimers with Various Carbon Skeletons from the Roots of Xylopia vielana  期刊论文  

  • 编号:
    760f98ed-7a48-4f58-a683-f80323d0eebc
  • 作者:
    Guo, YiGong#[1]Xie, YangGuo[1];Wu, GuoJing[1];Cheng, TaoFang[1];Zhu, ShengLan[1];Yan, ShiKai*[1]Jin, HuiZi*[1,3]Zhang, WeiDong*[1,2,3]
  • 语种:
    英文
  • 期刊:
    ACS OMEGA ISSN:2470-1343 2019 年 4 卷 1 期 (2047 - 2052) ; JAN
  • 收录:
  • 摘要:

    Five new guaiane dimers, xylopidimers A-E (1-5), were isolated and identified from the roots of Xylopia vielana. The structures of 1-5 were elucidated by spectroscopic analysis and further confirmed by single-crystal X-ray diffraction. On the basis of the results of single-crystal X-ray analysis, 1-5 showed different carbon skeletons. Among these compounds, the unique connecting patterns of 1 and 2 caused significant differences on their carbon skeletons, which have not been reported. Moreover, 3-5 were also three new guaiane dimers. Among these compounds, 4 exhibited potent inhibitory activity against the production of nitric oxide with an IC50 value of 4.59 mu M in RAW264.7 cells stimulated by lipopolysaccharide.

  • 推荐引用方式
    GB/T 7714:
    Guo Yi-Gong,Xie Yang-Guo,Wu Guo-Jing, et al. Xylopidimers A-E, Five New Guaiane Dimers with Various Carbon Skeletons from the Roots of Xylopia vielana [J].ACS OMEGA,2019,4(1):2047-2052.
  • APA:
    Guo Yi-Gong,Xie Yang-Guo,Wu Guo-Jing,Cheng Tao-Fang,&Zhang Wei-Dong.(2019).Xylopidimers A-E, Five New Guaiane Dimers with Various Carbon Skeletons from the Roots of Xylopia vielana .ACS OMEGA,4(1):2047-2052.
  • MLA:
    Guo Yi-Gong, et al. "Xylopidimers A-E, Five New Guaiane Dimers with Various Carbon Skeletons from the Roots of Xylopia vielana" .ACS OMEGA 4,1(2019):2047-2052.
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