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Molecular mechanism of vasculogenic mimicry in tumors 期刊论文

编号：

40d39199-5e09-4aa0-97a6-68204845fed0
作者：

Li, Wen^[1];Liu, Jianrong(刘见荣)^[1]Ren, Jianlin(任建琳)^[2]Li, Qi(李琦)^[3]Hou, Feng Gang(侯风刚)*^[1]
语种：

英文
期刊：

PIELEGNIARSTWO CHIRURGICZNE I ANGIOLOGICZNE-SURGICAL AND VASCULAR NURSING ISSN：1897-3116 2015 年 1 期 (22 - 27)
收录：
关键词：

vasculogenic mimicry (VM) molecular mechanism tumors
摘要：

Vasculogenic mimicry (VM) is a new model of tumor angiogenesis, which refers to the de novo formation of perfusable, matrix-rich, vasculogenic-like networks by virtue of the plasticity of aggressive tumor cells and the reconstruction of extracellular matrix (ECM). However, little is known about the molecular underpinnings of this phenomenon. To sum up, interactions of the critical VM-modulating pathways such as vascular (VE-cadherin, EphA2, VEGFR), embryonic and/or stem cell (Nodal, Notch4, CD133+, CD271), and hypoxia-related (HIF-1 alpha, Twist1) signaling pathways are necessary for the formation of vasculogenic mimicry. What is more, accompanied by anti-angiogenic therapy of tumors, the use of VM is becoming more and more important.
推荐引用方式
GB/T 7714：

Li Wen,Liu Jianrong,Ren Jianlin, et al. Molecular mechanism of vasculogenic mimicry in tumors [J].PIELEGNIARSTWO CHIRURGICZNE I ANGIOLOGICZNE-SURGICAL AND VASCULAR NURSING,2015(1):22-27.
APA：

Li Wen,Liu Jianrong,Ren Jianlin,Li Qi,&Hou Feng Gang.(2015).Molecular mechanism of vasculogenic mimicry in tumors .PIELEGNIARSTWO CHIRURGICZNE I ANGIOLOGICZNE-SURGICAL AND VASCULAR NURSING(1):22-27.
MLA：

Li Wen, et al. "Molecular mechanism of vasculogenic mimicry in tumors" .PIELEGNIARSTWO CHIRURGICZNE I ANGIOLOGICZNE-SURGICAL AND VASCULAR NURSING,1(2015):22-27.
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