Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a growing number of researchers have focused on the identification of target genes of lncRNAs. However, no online repository is available to collect the information on target genes regulated by lncRNAs. To make it convenient for researchers to know what genes are regulated by a lncRNA of interest, we developed a database named lncRNA2Target to provide a comprehensive resource of lncRNA target genes in 2015. To update the database this year, we retrieved all new lncRNA-target relationships from papers published from 1August 2014 to 30 April 2018 and RNA-seq datasets before and after knockdown or overexpression of a specific lncRNA. LncRNA2Target database v2.0 provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene, and is freely accessible at http://123.59.132.21/lncrna2target.
[1]Harbin Med Univ, Coll Bioinformat Sci & Technol, Harbin 150081, Heilongjiang, Peoples R China.
[2]Harbin Inst Technol, Sch Life Sci & Technol, Ctr Bioinformat, Harbin 150001, Heilongjiang, Peoples R China.
[3]Shanghai Univ Tradit Chinese Med, Longhua Hosp, Dept Radiol, Shanghai 200032, Peoples R China.
[4]Harbin Med Univ, Affiliated Hosp 2, Dept Radiol, Harbin 150086, Heilongjiang, Peoples R China.
(8.0+极速模式)