首页 / 院系成果 / 成果详情页

Research progress on signaling pathways in cirrhotic portal hypertension 期刊论文

编号：

2ed88e5b-5d97-41fa-8b18-e0b35d3e9e5a
作者：

Xu, Wen#^[1,2,3]Liu, Ping(刘平)^[1,2,3]Mu, YongPing(慕永平)*^[1,2,3]
语种：

英文
期刊：

WORLD JOURNAL OF CLINICAL CASES ISSN：2307-8960 2018 年 6 卷 10 期 (335 - 343) ; SEP 26
收录：
关键词：

PI3K-AKT-mTOR Portal hypertension Rhoassociated kinases Liver cirrhosis Signaling pathways Farnesoid X-activated receptors JAK2/STAT3
摘要：

Portal hypertension (PHT) is an important consequence of liver cirrhosis, which can lead to complications that adversely affect a patient's quality of life and survival, such as upper gastrointestinal bleeding, ascites, and portosystemic encephalopathy. In recent years, advances in molecular biology have led to major discoveries in the pathological processes of PHT, including the signaling pathways that may be involved: PI3K-AKT-mTOR, RhoA/Rho-kinase, JAK2/STAT3, and farnesoid X receptor. However, the pathogenesis of PHT is complex and there are numerous pathways involved. Therefore, the targeting of signaling pathways for medical management is lagging. This article summarizes the progress that has been made in understanding the signaling pathways in PHT, and provides ideas for treatment of the disorder.
推荐引用方式
GB/T 7714：

Xu Wen,Liu Ping,Mu Yong-Ping, et al. Research progress on signaling pathways in cirrhotic portal hypertension [J].WORLD JOURNAL OF CLINICAL CASES,2018,6(10):335-343.
APA：

Xu Wen,Liu Ping,Mu Yong-Ping.(2018).Research progress on signaling pathways in cirrhotic portal hypertension .WORLD JOURNAL OF CLINICAL CASES,6(10):335-343.
MLA：

Xu Wen, et al. "Research progress on signaling pathways in cirrhotic portal hypertension" .WORLD JOURNAL OF CLINICAL CASES 6,10(2018):335-343.
条目包含文件：

文件类型：PDF,文件大小：

正在加载全文

未找到全文

浏览次数：2  下载次数：0

分享到：

浏览次数：2

下载次数：0

打印次数：0