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Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial 期刊论文

编号：

2da9cb12-46a2-4706-bf4c-fcd3a43bd552
作者：

Cai, Yong#^[1]Xing, Guoqiang#*^[2,3]Shen, Tian^[1];Zhang, Shuxian^[1];Rao, Jianyu^[4];Shi, Rong(施榕)*^[5]
语种：

英文
期刊：

LIPIDS IN HEALTH AND DISEASE ISSN：1476-511X 2017 年 16 卷 ; DEC 22
收录：
关键词：

Citrus bergamia Extracts Body mass index Blood cholesterol Old adults
摘要：

Backgrounds: Recent experiments suggest that Citrus bergamia extracts could benefit people with dyslipidemia and obesity but this needs to be further validated.
Methods: A total of 98 people age-matched older adults (65 years) with elevated blood lipids were enrolled to receive 12-week supplementation of a Citrus bergamia extracts-based formulation (CitriCholess)(n = 48) and placebo (n = 50).
Results: No group differences were found in baseline bodyweight, body mass index (BMI), blood cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) and glucose levels. CitriCholess supplementation resulted in lower levels than placebo in TG (1.83 +/- 0.92 vs. 1.95 +/- 1.34 mmol/L, P = 0.612), TC (5.14 +/- 0.98 vs. 5.44 +/- 0.77 mmol/L, P = 0.097), and LDL-C (3.13 +/- 0.74 vs. 3.43 +/- 0.62 mmol/L, P = 0.032). Compared to placebo, CitriCholess also resulted in greater reductions in body weight (-0.604 +/- 0.939 vs. 0.06 +/- 0.74 kg, P < 0.01), waist circumferences (-0.60 +/- 1.349 cm vs. -0.16 +/- 1.503 cm, P < 0.01) and BMI (-0.207 +/- 0.357 vs. 0.025 +/- 0.274, P < 0.01). Additionally, females had a significantly higher level of HDL-C than males. TC was significantly correlated with LDL-C, and to a less degree, with TG. TG was inversely correlated with HDL-C. Body weight and waist circumference were negatively correlated with HDL-C and positively correlated with glucose.
Conclusion: 12-week supplementation of CitriCholess could benefit lipid metabolism and weight management in old adults with dyslipidemia.
推荐引用方式
GB/T 7714：

Cai Yong,Xing Guoqiang,Shen Tian, et al. Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial [J].LIPIDS IN HEALTH AND DISEASE,2017,16.
APA：

Cai Yong,Xing Guoqiang,Shen Tian,Zhang Shuxian,&Shi Rong.(2017).Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial .LIPIDS IN HEALTH AND DISEASE,16.
MLA：

Cai Yong, et al. "Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial" .LIPIDS IN HEALTH AND DISEASE 16(2017).
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