This article is aimed to present a design of a dynamic acupoint interior resistance detecting and analyzing system based on acupuncture therapeutic process. We applied detecting system of MCS-51 and precise microampere level constant current source as the main element to collect data, Labview soft to write host computer program, this system realize to detect dynamically acupoint interior resistance. The method avoided all the influencing factor of traditional detecting method. The result of elementary test show that the system has better repeatability and human acupoint internal resistance is related to individual difference, health condition and acupuncture therapeutic process. 漏 2013 IEEE.