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Scrodentoids F-I, four C-19-norditerpenoids from Scrophularia dentata 期刊论文

编号：

2691b5f1-da0c-4815-901b-f63a1e97cf99
作者：

Zhang, Liuqiang(张刘强)#^[1]Zhao, Yuanyuan^[1];Huang, Cheng(黄诚)^[1]Chen, Kaixian(陈凯先)^[1,2]Li, Yiming(李医明)*^[1]
语种：

英文
期刊：

TETRAHEDRON ISSN：0040-4020 2016 年 72 卷 49 期 (8031 - 8035) ; DEC 8
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关键词：

Scrophularia dentata C-19-Norditerpenoids Scrodentoids F-I X-ray crystallography FXR agonistic effect
摘要：

Four unprecedented C-19-diterpenoids, scrodentoids F-I (1-4), were isolated from the whole plant of Scrophularia dentata. Among them, scrodentoids H (3) and I (4) were identified to be a pair of epimerides. The structures and absolute configurations were elucidated through spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. Compounds 1-4 and scrodentoid B were tested for their farnesoid X-activate receptor agonistic effect. Compound 1 could moderately activate FXR transactivity in a dose-dependent manner. (C) 2016 Elsevier Ltd. All rights reserved.
推荐引用方式
GB/T 7714：

Zhang Liu-qiang,Zhao Yuan-yuan,Huang Cheng, et al. Scrodentoids F-I, four C-19-norditerpenoids from Scrophularia dentata [J].TETRAHEDRON,2016,72(49):8031-8035.
APA：

Zhang Liu-qiang,Zhao Yuan-yuan,Huang Cheng,Chen Kai-xian,&Li Yi-ming.(2016).Scrodentoids F-I, four C-19-norditerpenoids from Scrophularia dentata .TETRAHEDRON,72(49):8031-8035.
MLA：

Zhang Liu-qiang, et al. "Scrodentoids F-I, four C-19-norditerpenoids from Scrophularia dentata" .TETRAHEDRON 72,49(2016):8031-8035.
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