We observed a rare case of invasive mucinous adenocarcinoma (IMA) with a lepidic-predominant pattern accompanied by pulmonary tuberculosis. An 85-year-old man with repeated cough and sputum was admitted to Xinhua Hospital. T-SPOT test result was 212 pg/ml (reference value of negative is < 14 pg/ml), Mycobacterium tuberculosis culture was positive, and tuberculin skin test (PPD) was negative (skin induration < 5 mm). The patient was treated with several courses of antibiotics and anti-tuberculosis treatments. Repeated chest CT scans showed disease progression. Bronchoscopy yielded negative results. PET-CT scans showed negative results. A percutaneous lung biopsy revealed mucin-secreting cells lining the alveolar walls. IMA with a lepidic-predominant pattern was diagnosed after invasiveness was found after experimental treatments. Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present case of IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported yet.
[1]Shanghai Jiao Tong Univ, Xinhua Hosp, Dept Geriatr, Sch Med, Shanghai 200092, Peoples R China.
[2]Shanghai Jiao Tong Univ, Renji Hosp, Allergy Dept, Sch Med, Shanghai 200001, Peoples R China.
[3]Shanghai Univ Tradit Chinese Med, Putuo Hosp, Dept Intervent Radiol, Shanghai 200062, Peoples R China.
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